Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 7/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834014 | 0.81 | CCNE2 (0.44) | CCNE2CCNE1CDK2GABRA1GABRA5 | |
| SCHEMBL9381489 | 0.76 | GABRA1 (0.39) | CCNE2CCNE1CDK2CCKBRGABRA1 | |
| SCHEMBL9378707 | 0.75 | CYP11B1 (0.44) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL7428220 | 0.74 | PDPK1 (0.39) | JAK2 | |
| SCHEMBL11035945 | 0.71 | NISCH (0.60) | CCNE2CCNE1CDK2CCKBRGABRA1 | |
| SCHEMBL2782043 | 0.69 | NOS2 (0.39) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL1074100 | 0.69 | JAK2 (0.41) | CDK2CCKBRGABRA1GABRA5GABRA3 | |
| SCHEMBL8547651 | 0.69 | GABRA1 (0.73) | GABRA1GABRA5GABRA3GABRA2GABRB2 | |
| SCHEMBL5498994 | 0.67 | TNKS2 (0.36) | NISCH | |
| SCHEMBL5497321 | 0.67 | SMARCA2 (0.38) | JAK2NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |