SCHEMBL8774972

SCHEMBL8774972

NC(=O)CCCS(=O)(=O)CCCl

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8774985 0.88 APEX1 (0.44) APEX1
SCHEMBL9084614 0.82 APEX1 (0.54) APEX1
SCHEMBL1716661 0.82 ALDH1A1 (0.41) APEX1
SCHEMBL8774964 0.80 APEX1 (0.36) APEX1
SCHEMBL3359743 0.78 APEX1 (0.42) APEX1
SCHEMBL11683696 0.77 CA1 (0.31) APEX1
SCHEMBL10805112 0.76 NPC1 (0.36)
SCHEMBL9883956 0.76 LMNA (0.42) APEX1
SCHEMBL31513537 0.75 APEX1 (0.55) APEX1
SCHEMBL6637023 0.74 CA2 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5410027-A Diazotization of a protectively formylated hydroxyphenylenediamine; coupling with a hydrazone compound; metallization; reacting with a halotriazine BASF AKTIENGESELLSCHAFT (DE) 1995-04-25 US claimed
EP-0574799-B1 Method for the preparation of fibre-reactive formazana dyes as well as aminophenols BASF AG (DE) 1997-09-17 EP disclosed
US-5536876-A Formylamino-aminophenol compounds and their use in preparation of fiber-reactive formazan dyes BASF AKTIENGESELLSCHAFT (DE) 1996-07-16 US disclosed
US-5410027-A Diazotization of a protectively formylated hydroxyphenylenediamine; coupling with a hydrazone compound; metallization; reacting with a halotriazine BASF AKTIENGESELLSCHAFT (DE) 1995-04-25 US disclosed
EP-0574799-A2 Method for the preparation of fibre-reactive formazana dyes as well as aminophenols BASF Aktiengesellschaft (DE) 1993-12-22 EP disclosed
US-4908436-A Reactive dyes CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed