SCHEMBL8775066

SCHEMBL8775066

CCCCc1ccc(C=Cc2ccc(CCC3CCC(CCC)CC3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 3/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
HRH3 Q9Y5N1 2/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
TNNC1 P63316 1/20 0.37
SPHK2 Q9NRA0 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
HPGD P15428 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8775466 0.92 SPHK1 (0.40) SPHK1MAOAMAOBHRH3GRIN2D
SCHEMBL8775452 0.90 MAOB (0.49) MAOAMAOBHRH3CYP2C9TNNC1
SCHEMBL8015675 0.89 ALOX5 (0.41) MAOAMAOBHRH3CYP2C9NPC1
SCHEMBL8015686 0.89 ALOX5 (0.41) MAOAMAOBHRH3CYP2C9NPC1
SCHEMBL8015681 0.89 ALOX5 (0.41) MAOAMAOBHRH3CYP2C9NPC1
SCHEMBL8015678 0.89 ALOX5 (0.41) MAOAMAOBHRH3CYP2C9NPC1
SCHEMBL10724535 0.89 MAOA (0.45) SPHK1MAOAMAOBHRH3CYP3A4
SCHEMBL10724540 0.89 MAOA (0.45) SPHK1MAOAMAOBHRH3CYP3A4
SCHEMBL7906147 0.85 MAOA (0.43) SPHK1MAOAMAOBHRH3CYP3A4
SCHEMBL8433282 0.85 MAOA (0.43) SPHK1MAOAMAOBHRH3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1169138-A Novel liquid crystal compound bearing dienyl moiety and liquid crystal composition CHISSO CORP (JP) 1997-12-31 CN disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed