SCHEMBL8775466

SCHEMBL8775466

CCCCc1ccc(C=Cc2ccc(CCC3CCC(CC)CC3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 5/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
TNNC1 P63316 1/20 0.36
SPHK2 Q9NRA0 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
HPGD P15428 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8775066 0.92 SPHK1 (0.41) SPHK1MAOAMAOBGRIN2DGRIN3B
SCHEMBL8775428 0.88 ALOX5 (0.41) MAOAMAOBNPC1RAB9ASMN1; SMN2
SCHEMBL10718208 0.86 MAOA (0.42) SPHK1MAOAMAOBCYP3A4CA2
SCHEMBL9476473 0.83 MAOB (0.38) MAOAMAOB
SCHEMBL9476465 0.83 MAOB (0.38) MAOAMAOB
SCHEMBL8745621 0.83 TNNC1 (0.47) SPHK1CYP3A4CYP2D6CYP2C9TNNC1
SCHEMBL8775452 0.83 MAOB (0.49) MAOAMAOBCYP2C9TNNC1HRH3
SCHEMBL8040946 0.82 MAOB (0.43) SPHK1MAOAMAOBCA2CA1
SCHEMBL8454095 0.82 MAOB (0.43) SPHK1MAOAMAOBCA2CA1
SCHEMBL10718196 0.81 SPHK1 (0.44) SPHK1MAOAMAOBCYP3A4SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1169138-A Novel liquid crystal compound bearing dienyl moiety and liquid crystal composition CHISSO CORP (JP) 1997-12-31 CN disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed