Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775158 | 1.00 | GPR84 (0.34) | GPR84MAOBMAOAFFAR4HRH3 | |
| SCHEMBL8775089 | 0.93 | GPR84 (0.36) | GPR84MAOBMAOAFFAR4HRH3 | |
| SCHEMBL8775095 | 0.93 | GPR84 (0.36) | GPR84MAOBMAOAFFAR4HRH3 | |
| SCHEMBL8774629 | 0.93 | GPR84 (0.34) | GPR84MAOBMAOAFFAR4CNR1 | |
| SCHEMBL8774639 | 0.93 | GPR84 (0.34) | GPR84MAOBMAOAFFAR4CNR1 | |
| SCHEMBL8774407 | 0.92 | RARB (0.36) | GPR84MAOBMAOAFFAR4HRH3 | |
| SCHEMBL8774400 | 0.92 | RARB (0.36) | GPR84MAOBMAOAFFAR4HRH3 | |
| SCHEMBL8774424 | 0.89 | MAOB (0.38) | GPR84MAOBMAOAFFAR4HRH3 | |
| SCHEMBL8774417 | 0.89 | MAOB (0.38) | GPR84MAOBMAOAFFAR4HRH3 | |
| SCHEMBL8774814 | 0.86 | CYP2C9 (0.42) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |