Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775089 | 1.00 | GPR84 (0.36) | GPR84RARBHRH3KMT2ACTRC | |
| SCHEMBL8774400 | 0.97 | RARB (0.36) | GPR84RARBHRH3CTRCMAOA | |
| SCHEMBL8774407 | 0.97 | RARB (0.36) | GPR84RARBHRH3CTRCMAOA | |
| SCHEMBL8775158 | 0.93 | GPR84 (0.34) | GPR84RARBHRH3MAOAMAOB | |
| SCHEMBL8775154 | 0.93 | GPR84 (0.34) | GPR84RARBHRH3MAOAMAOB | |
| SCHEMBL8774629 | 0.91 | GPR84 (0.34) | GPR84MAOAMAOBFFAR4 | |
| SCHEMBL8774639 | 0.91 | GPR84 (0.34) | GPR84MAOAMAOBFFAR4 | |
| SCHEMBL8774103 | 0.90 | GPR84 (0.38) | GPR84RARBHRH3KMT2AMAOA | |
| SCHEMBL8774107 | 0.90 | GPR84 (0.38) | GPR84RARBHRH3KMT2AMAOA | |
| SCHEMBL8774504 | 0.86 | CYP2C9 (0.36) | KMT2AMEN1GAAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |