Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 8/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774671 | 0.90 | NPC1 (0.42) | FEN1ALOX5APGRM2GRIN1GRIN2B | |
| SCHEMBL8774995 | 0.87 | RARB (0.46) | GRM2 | |
| SCHEMBL8774917 | 0.86 | RARB (0.51) | — | |
| SCHEMBL8774831 | 0.85 | RARB (0.53) | HTR2A | |
| SCHEMBL8774251 | 0.85 | RARB (0.53) | HTR2A | |
| SCHEMBL8774839 | 0.84 | EGLN1 (0.45) | TDP1EGLN1 | |
| SCHEMBL9162398 | 0.83 | MAPT (0.39) | FEN1ALOX5APGRM2CHKAHTR2A | |
| SCHEMBL19007867 | 0.79 | RARB (0.43) | GRM2DGAT1CHKAHTR2A | |
| SCHEMBL13253648 | 0.79 | RARB (0.43) | GRM2DGAT1CHKAHTR2A | |
| SCHEMBL8774798 | 0.76 | FEN1 (0.40) | FEN1ALOX5APGRM2EGLN1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |