Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775220 | 1.00 | RAB9A (0.39) | RAB9AS1PR3CYP2C9HRH3LMNA | |
| SCHEMBL8774826 | 0.98 | RAB9A (0.40) | RAB9AS1PR3CYP2C9HRH3SPHK1 | |
| SCHEMBL8774816 | 0.98 | RAB9A (0.40) | RAB9AS1PR3CYP2C9HRH3SPHK1 | |
| SCHEMBL8774223 | 0.94 | RAB9A (0.35) | RAB9ACYP2C9HRH3LMNAMRGPRX4 | |
| SCHEMBL8774229 | 0.94 | RAB9A (0.35) | RAB9ACYP2C9HRH3LMNAMRGPRX4 | |
| SCHEMBL8774966 | 0.89 | MRGPRX4 (0.35) | RAB9ACYP2C9LMNAMRGPRX4KCNH2 | |
| SCHEMBL8774977 | 0.89 | MRGPRX4 (0.35) | RAB9ACYP2C9LMNAMRGPRX4KCNH2 | |
| SCHEMBL9766712 | 0.85 | SPHK1 (0.40) | RAB9AS1PR3CYP2C9HRH3LMNA | |
| SCHEMBL9158838 | 0.85 | SPHK1 (0.40) | RAB9AS1PR3CYP2C9HRH3LMNA | |
| SCHEMBL9158847 | 0.85 | SPHK1 (0.40) | RAB9AS1PR3CYP2C9HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519370-B1 | Heterocyclic derivatives | MERCK PATENT GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0519370-A2 | Heterocyclic derivatives | MERCK PATENT GmbH (DE) | 1992-12-23 | — | — | EP | disclosed |