Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158838 | 1.00 | SPHK1 (0.40) | SPHK1RAB9AS1PR3LMNAMAPT | |
| SCHEMBL9158847 | 1.00 | SPHK1 (0.40) | SPHK1RAB9AS1PR3LMNAMAPT | |
| SCHEMBL9159166 | 0.98 | RAB9A (0.41) | SPHK1RAB9AMAPTL3MBTL1CYP2C9 | |
| SCHEMBL9159174 | 0.98 | RAB9A (0.41) | SPHK1RAB9AMAPTL3MBTL1CYP2C9 | |
| SCHEMBL9875473 | 0.97 | RAB9A (0.38) | SPHK1RAB9AS1PR3LMNAMAPT | |
| SCHEMBL9875481 | 0.97 | RAB9A (0.38) | SPHK1RAB9AS1PR3LMNAMAPT | |
| SCHEMBL9160937 | 0.93 | ACACB (0.38) | RAB9ALMNAMAPTL3MBTL1CYP2C9 | |
| SCHEMBL9160931 | 0.93 | ACACB (0.38) | RAB9ALMNAMAPTL3MBTL1CYP2C9 | |
| SCHEMBL9158454 | 0.89 | MAPT (0.38) | RAB9ALMNAMAPTL3MBTL1CYP2C9 | |
| SCHEMBL9158447 | 0.89 | MAPT (0.38) | RAB9ALMNAMAPTL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |