SCHEMBL8775478

SCHEMBL8775478

CCc1ccc(C#Cc2ccc(C#CC3CCC(CC)CC3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.48
FFAR4 Q5NUL3 2/20 0.42
CYP2A6 P11509 1/20 0.39
ACACB O00763 8/20 0.36
PTGES O14684 1/20 0.34
RET P07949 1/20 0.34
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496202 0.90 FFAR1 (0.47) FFAR1FFAR4ACACBPTGESKCNH2
SCHEMBL9854903 0.90 FFAR1 (0.47) FFAR1FFAR4ACACBPTGESKCNH2
SCHEMBL8774981 0.88 FFAR1 (0.46) FFAR1FFAR4CYP2A6ACACBPTGES
SCHEMBL8775279 0.88 FFAR1 (0.52) FFAR1FFAR4ACACBPTGES
SCHEMBL8453446 0.84 FFAR1 (0.37) FFAR1FFAR4CYP2A6ACACBRET
SCHEMBL9497422 0.82 FFAR1 (0.42) FFAR1FFAR4ACACB
SCHEMBL9498077 0.82 FFAR1 (0.42) FFAR1FFAR4ACACBKCNH2
SCHEMBL9497432 0.82 FFAR1 (0.42) FFAR1FFAR4ACACB
SCHEMBL9498083 0.82 FFAR1 (0.42) FFAR1FFAR4ACACBKCNH2
SCHEMBL9497050 0.82 FFAR1 (0.50) FFAR1FFAR4ACACBPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1169138-A Novel liquid crystal compound bearing dienyl moiety and liquid crystal composition CHISSO CORP (JP) 1997-12-31 CN disclosed
EP-0805134-A1 NOVEL LIQUID-CRYSTAL COMPOUNDS BEARING DIENYL MOIETY AND LIQUID-CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-11-05 EP disclosed