Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12265911 | 0.96 | MAPT (0.44) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL8776080 | 0.94 | MAPT (0.43) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL12787008 | 0.93 | MAPT (0.43) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL12787013 | 0.93 | MAPT (0.43) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL12265918 | 0.93 | MEN1 (0.44) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL12147205 | 0.92 | MAPT (0.42) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL8775782 | 0.92 | MEN1 (0.42) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL14141068 | 0.92 | MAPT (0.44) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL13491013 | 0.92 | MAPT (0.41) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL13828516 | 0.92 | MAPT (0.42) | MAPTLMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501053-B2 | Multi color, photoactive, color changing compositions and UV dosimeters | BASF SE (DE) | 2013-08-06 | — | — | US | disclosed |
| US-8403558-B2 | TTI indicator with balanced photochemical processes | BIZERBA GMBH & CO. KG (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8403558-B2 | TTI indicator with balanced photochemical processes | BIZERBA GMBH & CO. KG (DE) | 2013-03-26 | — | — | US | disclosed |
| US-20130026428-A1 | PREPARATION OF A PHOTOCHROMIC INK | BASF SE (DE) | 2013-01-31 | — | — | US | disclosed |
| US-20120288690-A1 | MULTI COLOR, PHOTOACTIVE, COLOR CHANGING COMPOSITIONS | BASF SE (DE) | 2012-11-15 | — | — | US | disclosed |
| US-8287776-B2 | Preparation of a photochromic ink | BASF SE (DE) | 2012-10-16 | — | — | US | disclosed |
| EP-2102307-B1 | PHOTOSTABILIZED TIME TEMPERATURE INDICATOR | FRESHPOINT HOLDINGS SA (CH) | 2012-05-23 | — | — | EP | disclosed |
| US-20110297898-A1 | PREPARATION OF A PHOTOCHROMIC INK | BASF SE (DE) | 2011-12-08 | — | — | US | disclosed |
| US-20110297898-A1 | PREPARATION OF A PHOTOCHROMIC INK | BASF SE (DE) | 2011-12-08 | — | — | US | disclosed |
| US-20110217786-A1 | OPTIMIZED TIME TEMPERATURE INDICATOR | BIZERBA GMBH & CO. KG (DE) | 2011-09-08 | — | — | US | disclosed |
| US-20100135353-A1 | TTI INDICATOR WITH BALANCED PHOTOCHEMICAL PROCESSES | CIBA CORPORATION (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100135353-A1 | TTI INDICATOR WITH BALANCED PHOTOCHEMICAL PROCESSES | CIBA CORPORATION (US) | 2010-06-03 | — | — | US | disclosed |
| US-20100034961-A1 | PHOTOSTABILIZED TIME TEMPERATURE INDICATOR | FRESHPOINT HOLDINGS SA (CH) | 2010-02-11 | — | — | US | disclosed |
| US-20100034961-A1 | PHOTOSTABILIZED TIME TEMPERATURE INDICATOR | FRESHPOINT HOLDINGS SA (CH) | 2010-02-11 | — | — | US | disclosed |
| WO-2009127529-A1 | OPTIMIZED TIME TEMPERATURE INDICATOR | BASF SE (DE) | 2009-10-22 | — | — | WO | disclosed |
| WO-2008083895-A1 | TTI INDICATOR WITH BALANCED PHOTOCHEMICAL PROCESSES | CIBA HOLDING INC. (CH) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008083925-A1 | PHOTOSTABILIZED TIME TEMPERATURE INDICATOR | FRESHPOINT HOLDINGS SA (CH) | 2008-07-17 | — | — | WO | disclosed |
| US-20080167183-A1 | Light absorbing layer for photo-chromic systems | CIBA CORPORATION | 2008-07-10 | — | — | US | disclosed |
| US-20080167183-A1 | Light absorbing layer for photo-chromic systems | CIBA CORPORATION | 2008-07-10 | — | — | US | disclosed |
| WO-2008049755-A2 | LIGHT ABSORBING LAYER FOR PHOTO-CHROMIC SYSTEMS | CIBA HOLDING INC. (CH) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110297898-A1 | PREPARATION OF A PHOTOCHROMIC INK | RB1, REN, MYH14 | MAPT 1266/4885LMNA 299/4885MEN1 3052/4885 |
| US-20100034961-A1 | PHOTOSTABILIZED TIME TEMPERATURE INDICATOR | TTI1, NQO2, CCNI | MAPT 3732/4885LMNA 948/4885MEN1 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.