Sugi Predict

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SCHEMBL87757

SCHEMBL87757

O=C(O)c1cccc(C(=O)O)c1-c1ccccc1-c1ccccc1-c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HNF4A P41235 1/20 0.69
▸ ALDH1A1 P00352 3/20 0.61
▸ MAPT P10636 2/20 0.61
▸ LMNA P02545 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ FABP3 P05413 1/20 0.53
▸ FABP4 P15090 1/20 0.53
▸ FABP5 Q01469 1/20 0.53
▸ BCAT2 O15382 1/20 0.52
▸ MYC P01106 1/20 0.52
▸ ALOX15 P16050 1/20 0.50
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ GAA P10253 2/20 0.49
▸ GFER P55789 2/20 0.49
▸ NPC1 O15118 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87965 0.98 HNF4A (0.71) HNF4AALDH1A1MAPTLMNAL3MBTL1
Hydrochloric Acid SCHEMBL28366748 0.96 HNF4A (0.69) HNF4AALDH1A1MAPTLMNAL3MBTL1
SCHEMBL225203 0.86 HNF4A (0.71) HNF4AALDH1A1MAPTLMNAL3MBTL1
Benzene SCHEMBL28175839 0.85 HNF4A (0.64) HNF4AALDH1A1MAPTLMNAL3MBTL1
SCHEMBL30578395 0.85 HNF4A (0.64) HNF4AALDH1A1MAPTLMNAL3MBTL1
SCHEMBL3616574 0.85 ALDH1A1 (0.74) HNF4AALDH1A1MAPTLMNAL3MBTL1
SCHEMBL2346836 0.85 HNF4A (0.64) HNF4AALDH1A1MAPTLMNAL3MBTL1
SCHEMBL31278212 0.85 ALDH1A1 (0.74) HNF4AALDH1A1MAPTLMNAL3MBTL1
SCHEMBL31327312 0.84 HNF4A (0.63) HNF4AALDH1A1MAPTLMNAL3MBTL1
SCHEMBL31212508 0.84 HNF4A (0.63) HNF4AALDH1A1MAPTLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6239979-A — — None — — JP disclosed
JP-6239980-A — — None — — JP disclosed
US-10118169-B2 Chiral ligand-based metal-organic frameworks for broad-scope asymmetric catalysis THE UNIVERSITY OF CHICAGO (US) 2018-11-06 — — US disclosed
EP-3206987-A1 NANOPARTICLES FOR PHOTODYNAMIC THERAPY, X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF The University of Chicago (US) 2017-08-23 — — EP disclosed
US-20170173572-A1 CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-06-22 — — US disclosed
WO-2016061256-A1 NANOPARTICLES FOR PHOTODYNAMIC THERAPY, X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF THE UNIVERSITY OF CHICAGO (US) 2016-04-21 — — WO disclosed
WO-2013156227-A1 WEATHER RESISTANT POLYOXYMETHYLENE COMPOSITIONS TICONA GMBH (DE) 2013-10-24 — — WO disclosed
EP-2652001-A1 COUPLED GLASS-FIBER REINFORCED POLYOXYMETHYLENE Ticona GmbH (DE) 2013-10-23 — — EP disclosed
WO-2013149812-A1 TRIBOLOGICALLY MODIFIED POLYOXYMETHYLENE TICONA GMBH (DE) 2013-10-10 — — WO disclosed
WO-2013053914-A1 TRIBOLOGICALLY MODIFIED GLASS-FIBER REINFORCED POLYOXYMETHYLENE TICONA GMBH (DE) 2013-04-18 — — WO disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 — — US disclosed
EP-1978059-B1 HEAT-RESISTANT RESIN COMPOSITION, METHOD OF PRODUCING THE SAME, HEAT-RESISTANT RESIN MOLDED ARTICLE, AND SURFACE-MOUNT ELECTRONIC COMPONENT DAINIPPON INK & CHEMICALS (JP) 2010-08-25 — — EP disclosed
US-20090181234-A1 HEAT-RESISTANT RESIN COMPOSITION, METHOD OF PRODUCING THE SAME, HEAT-RESISTANT RESIN-MOLDED ARTICLE, AND SURFACE MOUNT ELECTRONIC COMPONENT DIC CORPORATION (JP) 2009-07-16 — — US disclosed
EP-1978059-A1 HEAT-RESISTANT RESIN COMPOSITION, METHOD FOR PRODUCTION THEREOF, HEAT-RESISTANT RESIN MOLDED ARTICLE, AND SURFACE-MOUNT ELECTRONIC ELEMENT DIC Corporation (JP) 2008-10-08 — — EP disclosed
EP-1347015-B1 Resin composition and molded product DAINIPPON INK & CHEMICALS (JP) 2005-09-21 — — EP disclosed
US-6677406-B2 Heat resistance; impact strength; dimensional stability; molding materials DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-01-13 — — US disclosed
US-20030187150-A1 Resin composition and molded product DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-10-02 — — US disclosed
EP-1347015-A1 Resin composition and molded product DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-09-24 — — EP disclosed
JP-H06239979-A POLYESTER AND MOLDED FORM USING THE SAME SANKO CHEM CO LTD 1994-08-30 — — JP disclosed
JP-H06239980-A POLYESTER AND MOLDED FORM USING THE SAME SANKO CHEM CO LTD 1994-08-30 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170173572-A1 CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS POF1B, FGFR1, COASY HNF4A 1271/4885ALDH1A1 861/4885MAPT 4198/4885
US-10118169-B2 Chiral ligand-based metal-organic frameworks for broad-scope asymmetric catalysis POF1B, FGFR1, COASY HNF4A 1271/4885ALDH1A1 861/4885MAPT 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.