SCHEMBL8775764

SCHEMBL8775764

CCOC(C=O)OCC=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418044 0.87
SCHEMBL768924 0.85 THRB (0.40) THRBLMNAALDH1A1MAPK1TDP1
SCHEMBL4276412 0.85 THRB (0.40) THRBLMNAALDH1A1MAPK1TDP1
SCHEMBL9019109 0.80
SCHEMBL9019014 0.80
SCHEMBL9019018 0.80
SCHEMBL8127935 0.80
SCHEMBL27335392 0.78
SCHEMBL28910125 0.78
SCHEMBL9446469 0.77 THRB (0.38) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807133-A1 A PROCESS FOR MAKING GRAFT BLOCK COPOLYMERS BY GRAFTING ANIONIC POLYMER CHAINS ONTO FUNCTIONALIZED POLYOLEFINS Montell Technology Company bv (NL) 1997-11-19 EP disclosed
US-5550194-A COPOLYMERIZING ALPHA-OLEFIN WITH 1-ALKENYL MONOMER HAVING FUNCTIONAL GROUP, ANIONICALLY POLYMERIZING MONOMER TO FORM LIVING POLYMER, GRAFTING LIVING POLYMER TO COPOLYMER TO FORM SATURATED BACKBONE POLYMER WITH ANIONIC SIDE CHAINS SHELL OIL COMPANY (US) 1996-08-27 US disclosed
WO-1996023824-A1 A PROCESS FOR MAKING GRAFT BLOCK COPOLYMERS BY GRAFTING ANIONIC POLYMER CHAINS ONTO FUNCTIONALIZED POLYOLEFINS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1996-08-08 WO disclosed