Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418044 | 0.97 | — | — | |
| SCHEMBL4276412 | 0.94 | THRB (0.40) | THRBLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL9446469 | 0.86 | THRB (0.38) | THRBLMNA | |
| SCHEMBL8775764 | 0.85 | THRB (0.33) | THRBLMNAALDH1A1MAPK1TDP1 | |
| SCHEMBL8127935 | 0.83 | — | — | |
| SCHEMBL28910125 | 0.81 | — | — | |
| SCHEMBL27335392 | 0.81 | — | — | |
| SCHEMBL10749712 | 0.79 | LMNA (0.38) | THRBLMNA | |
| SCHEMBL10543986 | 0.79 | TSHR (0.34) | ALDH1A1 | |
| SCHEMBL2215309 | 0.74 | TSHR (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264370-A | OF AN ALUMINUM ALKOXIDE WITH A LABILE MONOFUNCTIONAL REACTANT; STORAGE STABILITY | MANCHEM LIMITED (GB) | 1981-04-28 | — | — | US | claimed |
| US-9051473-B2 | Clear coating compositions comprising dispersed silica nono-particles and processes for using | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-8974898-B2 | Coated substrate having enhanced scratch and mar resistance | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2015-03-10 | — | — | US | disclosed |
| US-8937129-B2 | Rapid drying lacquers containing triblock copolymer for rheology control | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2015-01-20 | — | — | US | disclosed |
| US-8906461-B2 | Rapid drying lacquers containing triblock copolymer for rheology control | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8873918-B2 | Organosilica nanoparticles and method for making | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2014-10-28 | — | — | US | disclosed |
| US-8859050-B2 | Patterning of ultra-low refractive index high surface area nanoparticulate films | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130310510-A1 | RAPID DRYING LACQUERS CONTAINING IMPROVED RHEOLOGY CONTROL ADDITIVE | AXALTA COATING SYSTEMS IP CO LLC (US) | 2013-11-21 | — | — | US | disclosed |
| US-20120237677-A1 | PATTERNING OF ULTRA-LOW REFRACTIVE INDEX HIGH SURFACE AREA NANOPARTICULATE FILMS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2012-09-20 | — | — | US | disclosed |
| US-20120071682-A1 | ORGANOSILICA NANOPARTICLES AND METHOD FOR MAKING | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2012-03-22 | — | — | US | disclosed |
| US-20060100351-A1 | Rapid drying lacquers containing impoved rheology control additive | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-05-11 | — | — | US | disclosed |
| US-20060100350-A1 | Rapid drying lacquers containing graft copolymers with segmented arms | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-05-11 | — | — | US | disclosed |
| US-20060100353-A1 | Coating compositions for basecoats containing acrylic branched polymers | E.I. DU PONT DE NEMOURS AND COMPANY | 2006-05-11 | — | — | US | disclosed |
| US-6861495-B2 | Lacquers containing highly branched copolyester polyol | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-03-01 | — | — | US | disclosed |
| EP-1483347-A1 | LACQUERS CONTAINING HIGHLY BRANCHED COPOLYESTER POLYOL | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20030161961-A1 | Lacquers containing highly branched copolyester polyol | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2003-08-28 | — | — | US | disclosed |
| WO-2003070843-A1 | LACQUERS CONTAINING HIGHLY BRANCHED COPOLYESTER POLYOL | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-08-28 | — | — | WO | disclosed |
| US-RE31309-E | HYDROXYALKYL ACRYLATE MONOMER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
| US-4264370-A | OF AN ALUMINUM ALKOXIDE WITH A LABILE MONOFUNCTIONAL REACTANT; STORAGE STABILITY | MANCHEM LIMITED (GB) | 1981-04-28 | — | — | US | disclosed |
| US-4242243-A | HYDROXYALKYL ACRYLATE POLYMER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100351-A1 | Rapid drying lacquers containing impoved rheology control additive | STUB1, TECR, FOSB | THRB 1598/4885LMNA 4326/4885ALDH1A1 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.