Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775928 | 0.92 | TBXAS1 (0.60) | TBXAS1EPHX2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8775891 | 0.88 | TBXAS1 (0.62) | TBXAS1EPHX2TBXA2RSMN1; SMN2CYP2C9 | |
| SCHEMBL8775850 | 0.88 | TBXAS1 (0.48) | TBXAS1EPHX2NPC1RAB9ATP53 | |
| SCHEMBL8775863 | 0.87 | TBXAS1 (0.64) | TBXAS1EPHX2TBXA2RSMN1; SMN2CYP2C9 | |
| SCHEMBL8776095 | 0.87 | TBXAS1 (0.64) | TBXAS1EPHX2TBXA2RSMN1; SMN2CYP2C9 | |
| SCHEMBL8775780 | 0.87 | TBXAS1 (0.64) | TBXAS1EPHX2TBXA2RSMN1; SMN2CYP2C9 | |
| SCHEMBL8775884 | 0.87 | TBXAS1 (0.64) | TBXAS1EPHX2TBXA2RSMN1; SMN2CYP2C9 | |
| SCHEMBL8775861 | 0.84 | TBXAS1 (0.56) | TBXAS1EPHX2SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL8775800 | 0.82 | TBXAS1 (0.46) | TBXAS1EPHX2GRM8GRM4PDE4D | |
| SCHEMBL8775778 | 0.79 | KCNA5 (0.44) | TBXAS1EPHX2TBXA2RTP53TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |