Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775800 | 0.86 | TBXAS1 (0.46) | KCNA5TBXAS1KCNH2ROCK2EPHX2 | |
| SCHEMBL8775928 | 0.84 | TBXAS1 (0.60) | KCNA5TBXAS1EPHX2 | |
| SCHEMBL8775891 | 0.81 | TBXAS1 (0.62) | TBXAS1TBXA2REPHX2 | |
| SCHEMBL8775806 | 0.81 | KCNA5 (0.52) | KCNA5TBXAS1KCNH2PNMTROCK2 | |
| SCHEMBL8776095 | 0.80 | TBXAS1 (0.64) | TBXAS1TBXA2REPHX2 | |
| SCHEMBL8775863 | 0.80 | TBXAS1 (0.64) | TBXAS1TBXA2REPHX2 | |
| SCHEMBL8775884 | 0.80 | TBXAS1 (0.64) | TBXAS1TBXA2REPHX2 | |
| SCHEMBL8775780 | 0.80 | TBXAS1 (0.64) | TBXAS1TBXA2REPHX2 | |
| SCHEMBL8775772 | 0.79 | TBXAS1 (0.51) | TBXAS1TRPM8TBXA2RTP53EPHX2 | |
| SCHEMBL8775861 | 0.77 | TBXAS1 (0.56) | KCNA5TBXAS1KCNH2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |