Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775928 | 0.87 | TBXAS1 (0.60) | TBXAS1KCNA5EPHX2GRM8GRM4 | |
| SCHEMBL8775778 | 0.86 | KCNA5 (0.44) | TBXAS1KCNA5KCNH2EPHX2ROCK2 | |
| SCHEMBL8775891 | 0.83 | TBXAS1 (0.62) | TBXAS1EPHX2GRM8GRM4 | |
| SCHEMBL8775863 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2GRM8GRM4 | |
| SCHEMBL8776095 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2GRM8GRM4 | |
| SCHEMBL8775780 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2GRM8GRM4 | |
| SCHEMBL8775884 | 0.82 | TBXAS1 (0.64) | TBXAS1EPHX2GRM8GRM4 | |
| SCHEMBL8775772 | 0.82 | TBXAS1 (0.51) | TBXAS1EPHX2GRM8GRM4PDE4D | |
| SCHEMBL8775861 | 0.80 | TBXAS1 (0.56) | TBXAS1KCNA5KCNH2EPHX2GRM8 | |
| SCHEMBL8775850 | 0.79 | TBXAS1 (0.48) | TBXAS1KCNA5EPHX2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |