Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776036 | 0.80 | ALOX5 (0.52) | KCNA5SMN1; SMN2TBXAS1LMNAHPGD | |
| SCHEMBL8775894 | 0.77 | SLC7A5 (0.55) | KCNA5SMN1; SMN2LMNACYP2C9CYP2C19 | |
| SCHEMBL8775843 | 0.77 | SLC6A2 (0.46) | KCNA5SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31570747 | 0.77 | SLC6A2 (0.66) | KCNA5SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL884658 | 0.77 | KCNA5 (0.47) | KCNA5SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2063857 | 0.77 | KCNA5 (0.47) | KCNA5SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL884888 | 0.76 | CYP1A2 (0.54) | KCNA5SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL177932 | 0.75 | — | — | |
| SCHEMBL4098469 | 0.75 | — | — | |
| SCHEMBL31080226 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |