Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775839 | 0.77 | KCNA5 (0.48) | KCNA5LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8775896 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2ATDP1SMN1; SMN2GPR132 | |
| SCHEMBL27608960 | 0.76 | SLC7A5 (0.61) | SLC7A5ALDH1A1FOLH1LOXL2CASR | |
| SCHEMBL20168566 | 0.75 | SLC7A5 (0.76) | SLC7A5ALDH1A1FOLH1LOXL2CYP4F2 | |
| SCHEMBL3629091 | 0.74 | SIGMAR1 (0.60) | SLC7A5ALDH1A1FOLH1LOXL2CASR | |
| SCHEMBL4426418 | 0.74 | SIGMAR1 (0.60) | SLC7A5ALDH1A1FOLH1LOXL2CASR | |
| SCHEMBL15609359 | 0.74 | SIGMAR1 (0.60) | SLC7A5ALDH1A1FOLH1LOXL2CASR | |
| SCHEMBL8776036 | 0.74 | ALOX5 (0.52) | KCNA5LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL8775843 | 0.74 | SLC6A2 (0.46) | KCNA5LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL1790854 | 0.73 | SLC7A5 (0.68) | SLC7A5ALDH1A1FOLH1LOXL2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |