Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.53 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313089 | 0.85 | PDE4D (0.45) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4604382 | 0.83 | SLC6A3 (0.55) | SLC6A2SLC6A4SLC6A3SMN1; SMN2KDM4E | |
| SCHEMBL8775911 | 0.83 | TBXAS1 (0.56) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL68782 | 0.82 | HTR2A (0.46) | KDM4ECYP2C19 | |
| SCHEMBL2299246 | 0.82 | CFTR (0.53) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9312935 | 0.81 | PDE4D (0.40) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8775906 | 0.79 | TBXAS1 (0.63) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7043773 | 0.79 | CFTR (0.44) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27420791 | 0.78 | CFTR (0.49) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8775954 | 0.78 | TBXAS1 (0.66) | CFTRGOPCSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |