Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL7111631 | 0.87 | VCAM1 (0.36) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL713906 | 0.77 | BCAT2 (0.36) | HPGDALDH1A1BCAT2BCAT1LMNA | |
| SCHEMBL7033756 | 0.77 | BCAT2 (0.57) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL4301297 | 0.70 | MAPT (0.59) | VCAM1MAPTCYP1A2CYP2C9HPGD | |
| SCHEMBL1114152 | 0.69 | MAPT (0.60) | VCAM1MAPTCYP1A2POLBCYP2C9 | |
| SCHEMBL6920290 | 0.69 | VCAM1 (0.41) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL12733342 | 0.69 | MAPT (0.61) | VCAM1MAPTCYP1A2CYP2C9HPGD | |
| SCHEMBL11477482 | 0.67 | VCAM1 (0.68) | VCAM1MAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL82777 | 0.67 | MAPT (0.60) | VCAM1MAPTCYP2C9HPGDTDP1 | |
| SCHEMBL4804996 | 0.67 | KMT2A (0.47) | VCAM1MAPTGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808310-A1 | NOVEL 3-(4-CYANOPHENYL)URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024590-A1 | NOVEL 3-(4-CYANOPHENYL)URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-15 | — | — | WO | disclosed |