Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 10/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037750 | 0.81 | MAPT (0.36) | VCAM1BCAT2BCAT1CYP1A2GRIA1 | |
| SCHEMBL1574267 | 0.79 | AR (0.38) | VCAM1ARBCAT2BCAT1 | |
| SCHEMBL8694102 | 0.78 | GSK3A (0.42) | SIRT6MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL8002260 | 0.78 | AR (0.38) | ARBCAT2BCAT1 | |
| SCHEMBL8696659 | 0.77 | ABCC9 (0.38) | ARMAPTPGRSMN1; SMN2MEN1 | |
| SCHEMBL7033756 | 0.76 | BCAT2 (0.57) | VCAM1BCAT2BCAT1CYP1A2GRIA1 | |
| SCHEMBL9469308 | 0.76 | POLB (0.41) | ARBCAT2BCAT1MAPTKMT2A | |
| SCHEMBL8465633 | 0.76 | AR (0.37) | ARBCAT2BCAT1PGR | |
| SCHEMBL8190792 | 0.74 | AR (0.39) | ARBCAT2BCAT1PGR | |
| SCHEMBL3243992 | 0.74 | ALDH1A1 (0.38) | ARSIRT6CYP1A2MAPTPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004007467-A1 | NOVEL 3-(3-[AMINOSULFONYLAMINO]-4-CYANO-PHENYL)-6-TRIFLUOROMETHYL-URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-22 | — | — | WO | disclosed |