SCHEMBL8776056

SCHEMBL8776056

CCC(Cc1ccccc1)(C(=O)c1ccc(N(C)C)c(OC)c1)N(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.42
BCHE P06276 4/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 1/20 0.40
OPRM1 P35372 2/20 0.40
OPRD1 P41143 2/20 0.40
NR1I2 O75469 1/20 0.40
CHRM2 P08172 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADRA2B P18089 1/20 0.40
SLC6A4 P31645 1/20 0.40
OPRK1 P41145 1/20 0.40
CHRNA4 P43681 1/20 0.40
SLC6A3 Q01959 1/20 0.40
PDE4D Q08499 1/20 0.40
KCNH2 Q12809 1/20 0.40
HTT P42858 1/20 0.39
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421022 0.90 ACHE (0.53) ACHEBCHENPC1RAB9ASMN1; SMN2
SCHEMBL480430 0.90 ACHE (0.53) ACHEBCHENPC1RAB9ASMN1; SMN2
SCHEMBL21706301 0.85 ACHE (0.45) ACHEBCHENPC1RAB9ASMN1; SMN2
SCHEMBL8896911 0.85 KMT2A (0.35) HPGDALDH1A1MAPK1MAPTMEN1
SCHEMBL8898433 0.85 OPRM1 (0.53) ACHEBCHESMN1; SMN2HPGDOPRM1
SCHEMBL8176376 0.82 HPGD (0.47) ACHEBCHENPC1RAB9ASMN1; SMN2
SCHEMBL8179111 0.81 HPGD (0.46) ACHEBCHENPC1RAB9ASMN1; SMN2
SCHEMBL8175821 0.81 HPGD (0.46) ACHEBCHENPC1RAB9ASMN1; SMN2
SCHEMBL4651504 0.81 ACHE (0.51) ACHENPC1RAB9ASMN1; SMN2HPGD
SCHEMBL9315365 0.81 ACHE (0.51) ACHEBCHENPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0485334-B1 Photopolymerizable compositions TOKYO OHKA KOGYO CO LTD (JP) 1997-11-26 EP disclosed
US-5645974-A PHOTOPOLYMERIZATION INITIATOR COMPRISING BENZOYLAMINOBENZYLALKANE AND PHENYLDIALKOXYACETOPHENONE TOKYO OHKA KOGYO, K.K. (JP) 1997-07-08 US disclosed
US-5541038-A FOR THICK FILM PRINTING PLATES, MIXTURE OF PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1996-07-30 US disclosed
EP-0485334-A2 Photopolymerizable compositions TOKYO OHKA KOGYO CO., LTD. (JP) 1992-05-13 EP disclosed