Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179111 | 0.91 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL8175821 | 0.91 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL29421022 | 0.89 | ACHE (0.53) | HPGDNPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL480430 | 0.89 | ACHE (0.53) | HPGDNPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL21706301 | 0.83 | ACHE (0.45) | HPGDNPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL8776056 | 0.82 | ACHE (0.42) | HPGDNPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL9315365 | 0.81 | ACHE (0.51) | HPGDNPC1RAB9ASMN1; SMN2ACHE | |
| SCHEMBL8898433 | 0.80 | OPRM1 (0.53) | HPGDSMN1; SMN2ACHEBCHETHRB | |
| SCHEMBL9316355 | 0.79 | CTNNB1 (0.50) | ACHEBCHETSHRPOLB | |
| SCHEMBL4652464 | 0.78 | ACHE (0.47) | HPGDSMN1; SMN2ACHEBCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022906-A | α-aminoacetophenone photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-08 | — | — | US | disclosed |