SCHEMBL8776100

SCHEMBL8776100

Nc1cc2c(O)c(CS(=O)(=O)O)c(S(=O)(=O)O)cc2cc1S(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.36
CASP6 P55212 3/20 0.36
NSD2 O96028 2/20 0.36
GAA P10253 1/20 0.36
PLCG1 P19174 1/20 0.36
DNMT1 P26358 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 3/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NQO1 P15559 1/20 0.33
NT5E P21589 3/20 0.32
DUSP3 P51452 1/20 0.32
PTPN5 P54829 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649791 0.84 NT5E (0.50) TTRCASP6NSD2GAAL3MBTL1
SCHEMBL14339180 0.79 ALDH1A1 (0.38) TTRCASP6NSD2GAAPLCG1
SCHEMBL4650426 0.77 CA2 (0.35) CA2CA3
SCHEMBL7754466 0.77 AURKA (0.42) TTRAURKAAURKBALDH1A1HSD17B10
SCHEMBL27503783 0.73 NSD2 (0.43) NSD2ALDH1A1TDP1CYP2C9
SCHEMBL4650356 0.73 NT5E (0.38) CASP6NSD2CASP7NT5EDUSP3
SCHEMBL14339194 0.73 CA2 (0.40) CASP6ALDH1A1HSD17B10CASP1CASP7
SCHEMBL14339179 0.72 ALDH1A1 (0.33) TTRCASP6NSD2GAAPLCG1
SCHEMBL9331048 0.71 AURKA (0.53) TTRCASP6AURKAAURKBALDH1A1
SCHEMBL600908 0.70 TTR (0.59) TTRCASP6GAAAURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0798347-A1 Reactive monoazo dyes with a diazo compound derived from 5-substituted sulfanilic acid BASF AKTIENGESELLSCHAFT (DE) 1997-10-01 EP disclosed