Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.34 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.34 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047153 | 0.81 | AURKA (0.45) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL2615797 | 0.79 | AURKA (0.44) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL8752857 | 0.77 | TTR (0.36) | AURKBTTRCYP1A2CYP2C9MAPK1 | |
| SCHEMBL8776100 | 0.77 | TTR (0.36) | AURKAAURKBTTRCYP1A2SENP2 | |
| SCHEMBL14290611 | 0.76 | CYP1A2 (0.48) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL4649791 | 0.75 | NT5E (0.50) | AURKAAURKBTTRSENP2SUMO2 | |
| SCHEMBL7027692 | 0.75 | AURKA (0.53) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL4763755 | 0.74 | TTR (0.46) | AURKAAURKBTTRCYP1A2PHLPP2 | |
| SCHEMBL11433276 | 0.74 | AURKA (0.47) | AURKAAURKBTTRCYP1A2GLO1 | |
| SCHEMBL28041867 | 0.73 | TTR (0.45) | AURKAAURKBTTRCYP1A2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086180-A1 | TRISAZO AND POLYAZO DYES AND THE MIXTURES THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064520-A1 | TRISAZO AND POLYAZO DYES AND THE MIXTURES THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-16 | — | — | WO | disclosed |