Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776134 | 0.80 | ATM (0.44) | CYP2C9ATMCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL4686790 | 0.73 | LMNA (0.48) | CYP2C9LMNAALDH1A1 | |
| SCHEMBL4687373 | 0.73 | LMNA (0.48) | CYP2C9LMNAALDH1A1 | |
| SCHEMBL4688167 | 0.73 | LMNA (0.48) | CYP2C9LMNAALDH1A1 | |
| SCHEMBL8608582 | 0.73 | ATM (0.38) | CYP2C9ATMCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL4687385 | 0.71 | LMNA (0.47) | CYP2C9LMNAALDH1A1 | |
| SCHEMBL22875371 | 0.71 | CYP1A2 (0.57) | ATMCYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL4688379 | 0.71 | LMNA (0.47) | CYP2C9LMNAALDH1A1 | |
| SCHEMBL9408451 | 0.71 | ATM (0.42) | CYP2C9LMNAATMCYP1A2CYP2D6 | |
| SCHEMBL24132476 | 0.70 | CYP1A2 (0.48) | CYP2C9ATMCYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570263-B1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR (FR) | 1997-12-03 | — | — | EP | disclosed |
| US-5436343-A | Thromboxane A2 receptor antagonist, thromoboxane A2 synthase inhibitor | ADIR ET COMPAGNIE (FR) | 1995-07-25 | — | — | US | disclosed |
| EP-0570263-A1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-11-18 | — | — | EP | disclosed |