Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776167 | 0.80 | CYP2C9 (0.42) | ATMCYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL9408451 | 0.78 | ATM (0.42) | ATMCYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL13593718 | 0.78 | ESR2 (0.34) | — | |
| SCHEMBL24132476 | 0.73 | CYP1A2 (0.48) | ATMCYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL286913 | 0.73 | TSHR (0.42) | CYP2C9 | |
| SCHEMBL6513894 | 0.73 | — | — | |
| SCHEMBL8608582 | 0.73 | ATM (0.38) | ATMCYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL13593724 | 0.72 | CYP1A2 (0.42) | CYP1A2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6519607 | 0.71 | CA1 (0.30) | — | |
| SCHEMBL13423998 | 0.70 | OPRM1 (0.42) | ATMCYP1A2CYP2D6ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570263-B1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR (FR) | 1997-12-03 | — | — | EP | disclosed |
| US-5436343-A | Thromboxane A2 receptor antagonist, thromoboxane A2 synthase inhibitor | ADIR ET COMPAGNIE (FR) | 1995-07-25 | — | — | US | disclosed |
| EP-0570263-A1 | New alkene carboxylic acid derivatives, process for their preparation and pharmaceutic compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-11-18 | — | — | EP | disclosed |