Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13423998 | 0.83 | OPRM1 (0.42) | ATMALDH1A1GAAMAPTUSP2 | |
| SCHEMBL8776134 | 0.78 | ATM (0.44) | ATMALDH1A1GAAMAPTUSP2 | |
| SCHEMBL12332480 | 0.77 | CRBN (0.46) | ALDH1A1CYP2C19KDM4ELMNANPSR1 | |
| SCHEMBL24132476 | 0.75 | CYP1A2 (0.48) | ATMALDH1A1GAAMAPTUSP2 | |
| SCHEMBL8608582 | 0.74 | ATM (0.38) | ATMALDH1A1GAAMAPTUSP2 | |
| SCHEMBL19585725 | 0.72 | CRBN (0.44) | ALDH1A1MAPTCYP2C19KDM4ELMNA | |
| SCHEMBL8776167 | 0.71 | CYP2C9 (0.42) | ATMALDH1A1CYP1A2CYP2D6ALOX15 | |
| SCHEMBL25477463 | 0.70 | CYP1A2 (0.39) | ALDH1A1GAAMAPTUSP2CYP1A2 | |
| SCHEMBL19628662 | 0.70 | ALDH1A1 (0.39) | ATMALDH1A1GAAMAPTUSP2 | |
| SCHEMBL26880822 | 0.69 | ATM (0.38) | ATMALDH1A1CYP1A2CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621267-A1 | Spiropiperidine derivatives and their use as fungicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1994-10-26 | — | — | EP | disclosed |