Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 10/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 7/20 | 0.36 |
| ▸ | CTSS | P25774 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307743 | 0.87 | CTSK (0.44) | SSTR4CTSKCTSSCTSLCTSB | |
| SCHEMBL7357403 | 0.82 | CTSS (0.51) | SSTR4CTSKCTSSCTSLCTSB | |
| SCHEMBL28908633 | 0.81 | SSTR4 (0.41) | SSTR4CTSKCTSSCTSLCTSB | |
| SCHEMBL6843350 | 0.80 | SSTR4 (0.39) | SSTR4CTSKCTSSCTSLCTSB | |
| SCHEMBL28576006 | 0.77 | SSTR4 (0.43) | SSTR4 | |
| SCHEMBL31252251 | 0.75 | IDO1 (0.43) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL31252212 | 0.74 | CTSK (0.38) | SSTR4HDAC4HDAC1HDAC6CTSK | |
| SCHEMBL31252121 | 0.72 | CYP1A2 (0.46) | SSTR4HDAC4HDAC1HDAC6CTSK | |
| SCHEMBL28672224 | 0.72 | MEN1 (0.41) | SSTR4CA1CA2 | |
| SCHEMBL28352490 | 0.72 | SSTR4 (0.39) | SSTR4CTSKCTSSCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808455-A1 | APPLICATION OF COUNTERCURRENT CHROMATOGRAPHY TO THE DECONVOLUTION OF CHEMICAL LIBRARIES | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024842-A1 | APPLICATION OF COUNTERCURRENT CHROMATOGRAPHY TO THE DECONVOLUTION OF CHEMICAL LIBRARIES | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |