Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776174 | 0.87 | SSTR4 (0.39) | CTSKCTSLCTSSCTSBSSTR4 | |
| SCHEMBL19619076 | 0.82 | CTSK (0.56) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL19851480 | 0.82 | CTSK (0.56) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL28908633 | 0.82 | SSTR4 (0.41) | CTSKCTSLCTSSCTSBSSTR4 | |
| SCHEMBL7357403 | 0.81 | CTSS (0.51) | CTSKCTSLCTSSCTSBSSTR4 | |
| SCHEMBL4185679 | 0.80 | CTSS (0.52) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL6843350 | 0.79 | SSTR4 (0.39) | CTSKCTSLCTSSCTSBSSTR4 | |
| SCHEMBL28576006 | 0.76 | SSTR4 (0.43) | SSTR4 | |
| SCHEMBL31252251 | 0.74 | IDO1 (0.43) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL28352490 | 0.74 | SSTR4 (0.39) | CTSKCTSSGAASSTR4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |