Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877186 | 0.75 | TNF (0.39) | — | |
| SCHEMBL877634 | 0.69 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL892139 | 0.67 | BACE1 (0.39) | BACE1CTSD | |
| SCHEMBL12470247 | 0.55 | EIF2AK2 (0.54) | — | |
| SCHEMBL16648351 | 0.54 | DRD2 (0.37) | — | |
| SCHEMBL2094667 | 0.54 | RXRB (0.47) | — | |
| SCHEMBL23519750 | 0.53 | BRD4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL4715513 | 0.53 | DRD2 (0.36) | — | |
| SCHEMBL2090132 | 0.53 | RXRA (0.50) | — | |
| SCHEMBL878160 | 0.53 | ACHE (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040641-A2 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2012-03-29 | — | — | WO | disclosed |