Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 18/20 | 0.83 |
| ▸ | RARG | P13631 | 18/20 | 0.83 |
| ▸ | RARA | P10276 | 15/20 | 0.83 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.83 |
| ▸ | RXRA | P19793 | 3/20 | 0.54 |
| ▸ | RXRB | P28702 | 3/20 | 0.54 |
| ▸ | RXRG | P48443 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302926 | 0.91 | RARB (1.00) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL29353973 | 0.91 | RARB (1.00) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9006875 | 0.84 | RARB (0.64) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9176637 | 0.84 | RARB (0.64) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8776544 | 0.82 | RARB (0.65) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9484699 | 0.82 | RARB (0.69) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9007036 | 0.81 | RARB (0.60) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9484205 | 0.81 | RARB (0.67) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9483506 | 0.81 | RARB (0.67) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9180357 | 0.81 | RARB (0.60) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-5256694-A | For skin disorders; carcinomas | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-26 | — | — | US | disclosed |
| US-5126371-A | Precancerous skin conditions, acne, psoriasis | BASF AKTEINGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |
| US-4994489-A | Ester derivatives of diarylacetylenes, their compositions and their use in acne treatment | BASF AKTIENGESELLSCHAFT | 1991-02-19 | — | — | US | disclosed |
| US-4806558-A | Diarylacetylenes and their use in treating acne | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |