Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550242 | 0.91 | PDE10A (0.55) | HTTGAAMAPTNPSR1KDM4E | |
| SCHEMBL218739 | 0.87 | MAPT (0.63) | HTTGAAMAPTNPSR1KDM4E | |
| SCHEMBL7918712 | 0.84 | ALDH1A1 (0.68) | HTTGAAMAPTNPSR1ALDH1A1 | |
| SCHEMBL641899 | 0.82 | PDE10A (0.66) | MAPTKDM4EGLAALDH1A1PDE10A | |
| SCHEMBL29377848 | 0.82 | PDE10A (0.66) | MAPTKDM4EGLAALDH1A1PDE10A | |
| SCHEMBL28673884 | 0.81 | PDE10A (0.51) | HTTGAAMAPTNPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL1603404 | 0.80 | PDE10A (0.63) | HTTGAAMAPTKDM4EGLA | |
| Iodide SCHEMBL8029601 | 0.80 | PDE10A (0.63) | MAPTKDM4EGLAALDH1A1PDE10A | |
| Water SCHEMBL2991911 | 0.80 | PDE10A (0.63) | HTTGAAMAPTKDM4EGLA | |
| Iodide SCHEMBL8029606 | 0.80 | PDE10A (0.63) | MAPTKDM4EGLAALDH1A1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503076-B1 | PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOPOLYMERIZABLE ELEMENT | HITACHI CHEMICAL CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5334484-A | Using an acridine compound as photoinitiator | HITACHI CHEMICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0305545-B1 | SUBSTITUTED ACRIDINE DERIVATIVES AND THEIR USE | Hitachi Chemical Co., Ltd. (JP) | 1993-02-10 | — | — | EP | disclosed |
| EP-0503076-A1 | PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOPOLYMERIZABLE ELEMENT | HITACHI CHEMICAL CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5089377-A | Acridin-9-yl acrylates | ASAHI DENKA KOGYO K.K. (JP) | 1992-02-18 | — | — | US | disclosed |
| US-5045433-A | Photopolymerization initiators | HITACHI CHEMICAL CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| US-4985564-A | Acridine compound and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0360443-A1 | Acridine compound and photopolymerizable composition using the same | Hitachi Chemical Co., Ltd. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0305545-A1 | SUBSTITUTED ACRIDINE DERIVATIVES AND THEIR USE | Hitachi Chemical Co., Ltd. (JP) | 1989-03-08 | — | — | EP | disclosed |