SCHEMBL8776546

SCHEMBL8776546

NC(=S)NO[PH](=O)ONC(N)=S

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
PTGS2 P35354 1/20 0.35
HPGD P15428 1/20 0.35
TAS2R38 P59533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15390632 0.73 TSHR (0.37)
SCHEMBL1083263 0.73
SCHEMBL5455829 0.67
SCHEMBL11497076 0.67
SCHEMBL10393977 0.67 TAS2R38 (0.39) ALDH1A1HSD17B10PTGS2HPGDTAS2R38
SCHEMBL27304829 0.63
SCHEMBL27262972 0.63 ALDH1A1 (0.47) ALDH1A1HSD17B10PTGS2HPGDTAS2R38
SCHEMBL11113783 0.63
SCHEMBL7894024 0.63
SCHEMBL10717584 0.63 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601703-A Chirality oliopeptide phosphonate thiourea derivatives and application and preparation method thereof UNIV GUIZHOU MEDICAL 2016-05-25 CN disclosed
CN-105601703-A Chirality oliopeptide phosphonate thiourea derivatives and application and preparation method thereof UNIV GUIZHOU MEDICAL 2016-05-25 CN disclosed
EP-0600301-B1 Viscous coupling fluids DOW CORNING ASIA LTD (JP) 1997-12-03 EP disclosed
US-5374363-A Mixture of a polysiloxane as base oil, sulfur compound and a cyclic polysiloxane DOW CORNING ASIA, LTD. (JP) 1994-12-20 US disclosed
EP-0600301-A1 Viscous coupling fluids DOW CORNING ASIA, Ltd. (JP) 1994-06-08 EP disclosed