Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785974 | 0.89 | ALDH1A1 (0.46) | CYP1A2KDM4EALDH1A1MAPK1PDE10A | |
| SCHEMBL29360950 | 0.89 | ALDH1A1 (0.46) | CYP1A2KDM4EALDH1A1MAPK1PDE10A | |
| SCHEMBL30094573 | 0.89 | S1PR1 (0.38) | CYP1A2FAAHS1PR1TLR8KDM4E | |
| SCHEMBL27175932 | 0.89 | S1PR1 (0.38) | CYP1A2FAAHS1PR1TLR8KDM4E | |
| SCHEMBL8776630 | 0.88 | PDE10A (0.46) | CYP1A2FAAHS1PR1TLR8PDE10A | |
| SCHEMBL8777022 | 0.87 | CYP1A2 (0.46) | CYP1A2PDE10AKITNPC1MAPT | |
| SCHEMBL3789618 | 0.86 | CYP1A2 (0.45) | CYP1A2KDM4EALDH1A1MAPK1PDE10A | |
| SCHEMBL30129477 | 0.86 | CYP1A2 (0.45) | CYP1A2KDM4EALDH1A1MAPK1PDE10A | |
| SCHEMBL8775925 | 0.85 | S1PR1 (0.41) | CYP1A2FAAHS1PR1TLR8KDM4E | |
| SCHEMBL3785988 | 0.83 | CYP1A2 (0.45) | CYP1A2PDE10ANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200079801-A1 | TRISUBSTITUTEDSILYLBENZYLBENZIMIDAZOLES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-03-12 | — | — | US | disclosed |
| WO-2012069652-A2 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079801-A1 | TRISUBSTITUTEDSILYLBENZYLBENZIMIDAZOLES AND ANALOGUES | PIK3C3, DPM1, ERG28 | CYP1A2 110/4885FAAH 4356/4885S1PR1 3166/4885 |
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | CYP1A2 18/4885FAAH 3732/4885S1PR1 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.