Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.60 |
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101056 | 0.92 | CNR1 (0.61) | CNR1CNR2PTGS2PTGS1SQOR | |
| SCHEMBL8093740 | 0.91 | CNR1 (0.60) | CNR1CNR2PTGS2PTGS1SQOR | |
| SCHEMBL8776720 | 0.87 | PTGS2 (0.47) | CNR1CNR2PTGS2PTGS1SQOR | |
| SCHEMBL8095103 | 0.86 | CNR1 (0.61) | CNR1CNR2PTGS2PTGS1 | |
| SCHEMBL8086461 | 0.84 | CNR1 (0.61) | CNR1CNR2PTGS2PTGS1 | |
| SCHEMBL8086096 | 0.82 | CNR1 (0.69) | CNR1CNR2PTGS2PTGS1 | |
| SCHEMBL8776822 | 0.81 | PTGS2 (0.56) | CNR1CNR2PTGS2PTGS1SQOR | |
| SCHEMBL8086786 | 0.81 | CNR1 (0.64) | CNR1PTGS2PTGS1 | |
| SCHEMBL8101395 | 0.81 | CNR1 (0.55) | CNR1CNR2PTGS2PTGS1 | |
| SCHEMBL8095797 | 0.80 | CNR1 (0.69) | CNR1CNR2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024584-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |