Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279749 | 0.81 | TSHR (0.49) | ALDH1A1TSHRKMT2AMEN1CYP2C9 | |
| SCHEMBL8776703 | 0.80 | CYP2C9 (0.42) | ALDH1A1TSHRKMT2AMEN1CYP2C9 | |
| SCHEMBL4124999 | 0.79 | KMT2A (0.44) | ALDH1A1TSHRKMT2AGAAMEN1 | |
| SCHEMBL23581415 | 0.73 | AVPR1A (0.59) | OPRD1OPRK1CYP2C9CYP2C19 | |
| SCHEMBL27820393 | 0.73 | SIGMAR1 (0.46) | ALDH1A1TSHRKMT2AMEN1CYP2C9 | |
| SCHEMBL4130873 | 0.72 | CYP2D6 (0.43) | ALDH1A1TSHRKMT2AGAAMEN1 | |
| SCHEMBL14304647 | 0.72 | OPRD1 (0.48) | OPRD1OPRK1TSHRKDM4EGAA | |
| Hydrochloric Acid SCHEMBL27839717 | 0.72 | SIGMAR1 (0.45) | OPRD1ALDH1A1TSHRKMT2AMEN1 | |
| Diphenylmethane SCHEMBL28522550 | 0.71 | LTA4H (0.64) | LTA4HOPRD1OPRK1ALDH1A1KMT2A | |
| SCHEMBL8347656 | 0.71 | SLC6A2 (0.53) | ALDH1A1TSHRKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799202-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1997-10-08 | — | — | EP | disclosed |