Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 7/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086786 | 0.67 | CNR1 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7682212 | 0.67 | HPGD (0.55) | SQORADORA1MAPTALOX5KDM4E | |
| SCHEMBL8776738 | 0.66 | PTGS2 (0.50) | SQORMAPTPTGS2PTGS1ALOX5 | |
| SCHEMBL6904881 | 0.65 | PTGS2 (0.68) | PTGS2PTGS1ALOX5KDM4EALDH1A1 | |
| SCHEMBL845509 | 0.65 | SQOR (0.46) | SQORMAPTKDM4EALDH1A1POLB | |
| SCHEMBL7844215 | 0.64 | PTGS2 (0.55) | PTGS2PTGS1ALOX5 | |
| SCHEMBL7840986 | 0.64 | PTGS2 (0.55) | PTGS2PTGS1ALOX5 | |
| SCHEMBL16402615 | 0.64 | SQOR (0.44) | SQORKDM4EAR | |
| SCHEMBL845322 | 0.64 | SQOR (0.44) | SQORMAPTKDM4EALDH1A1 | |
| SCHEMBL845823 | 0.64 | SQOR (0.39) | SQORALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024584-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-08-15 | — | — | WO | disclosed |