Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087025 | 0.88 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8101739 | 0.78 | MAPK13 (0.54) | PTGS2PTGS1MAPK13MAPK12MAPK11 | |
| SCHEMBL8776749 | 0.78 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL8095222 | 0.78 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL215180 | 0.77 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL8098348 | 0.77 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL8098107 | 0.77 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL2932218 | 0.76 | CNR1 (0.49) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL8094036 | 0.76 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL212410 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-A1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-11-26 | — | — | EP | disclosed |