Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8414986 | 0.91 | ACACB (0.57) | PDE7AFFAR1CYP19A1GLASMN1; SMN2 | |
| SCHEMBL2511362 | 0.90 | PDE7A (0.55) | PDE7AFFAR1GLASMN1; SMN2ACACB | |
| SCHEMBL8417842 | 0.87 | PDE7A (0.52) | PDE7AFFAR1GLASMN1; SMN2ACACB | |
| SCHEMBL4318630 | 0.83 | PDE7A (0.63) | PDE7ASMN1; SMN2MAOAMAOBGFER | |
| SCHEMBL13742641 | 0.82 | FFAR1 (0.56) | PDE7AFFAR1SMN1; SMN2ACACB | |
| SCHEMBL554810 | 0.80 | MAOA (0.61) | PDE7AFFAR1SMN1; SMN2MAOAMAOB | |
| SCHEMBL8904604 | 0.80 | PDE7A (0.59) | PDE7ASMN1; SMN2MAOAMAOBGFER | |
| SCHEMBL11118950 | 0.80 | SMN1; SMN2 (0.49) | PDE7AFFAR1GLASMN1; SMN2ACACB | |
| SCHEMBL21186209 | 0.77 | PDE7A (0.56) | PDE7ASMN1; SMN2MAOAMAOBGFER | |
| SCHEMBL31264488 | 0.77 | PDE7A (0.56) | PDE7ASMN1; SMN2MAOAMAOBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604885-B1 | Liquid crystal display device | HOECHST AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5437813-A | A thin alignment layer comprising an aromatic polyamide-polysiloxane block homo- or copolymer with different content of polysiloxane to adjust optical pretilt angle | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-01 | — | — | US | disclosed |
| EP-0604885-A1 | Liquid crystal display device | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-06 | — | — | EP | disclosed |