Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264488 | 1.00 | PDE7A (0.56) | PDE7AMAOAMAOBALDH1A1CYP3A4 | |
| SCHEMBL21186018 | 0.89 | PDE7A (0.47) | PDE7AALDH1A1SLC6A4HTR2AKCNH2 | |
| SCHEMBL2812244 | 0.86 | MAOB (0.47) | PDE7AMAOAMAOBALDH1A1CYP3A4 | |
| SCHEMBL4318630 | 0.85 | PDE7A (0.63) | PDE7AMAOAMAOBALDH1A1CYP3A4 | |
| SCHEMBL15955628 | 0.82 | SLC6A4 (0.44) | PDE7ASLC6A4HTR2AKCNH2SLC6A2 | |
| SCHEMBL4374841 | 0.81 | HSPB1 (0.58) | MAOAMAOBALDH1A1CYP3A4TSHR | |
| SCHEMBL8904604 | 0.81 | PDE7A (0.59) | PDE7AMAOAMAOBALDH1A1CYP3A4 | |
| SCHEMBL554810 | 0.81 | MAOA (0.61) | PDE7AMAOAMAOBALDH1A1CYP3A4 | |
| SCHEMBL11018978 | 0.81 | ALDH1A1 (0.50) | PDE7AALDH1A1SLC6A4HTR2AKCNH2 | |
| SCHEMBL4367987 | 0.81 | ST14 (0.50) | MAOBSLC6A4HTR2AKCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| EP-4504712-A1 | GPR35 MODULATORS AND USES THEREOF | Crossignal Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196538-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | GPR35, GPR34, GPR68 | PDE7A 2644/4885MAOA 3766/4885MAOB 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.