Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | ESR1 | P03372 | 3/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | UQCRB | P14927 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26268 | 0.85 | PKM (0.65) | ELANEGAAPKMPOLBKMT2A | |
| SCHEMBL12541779 | 0.84 | ESR1 (0.53) | ESR2ESR1ALDH1A1CYP3A4PTPN5 | |
| SCHEMBL24513216 | 0.82 | HTT (0.51) | HSD11B1ALDH1A1PTPN5CNR2HTT | |
| SCHEMBL4613497 | 0.81 | HTR6 (0.54) | GAAPKMALDH1A1CNR2POLB | |
| SCHEMBL17146887 | 0.79 | NR1H4 (0.50) | ELANEGAAPKMHSD11B1ALDH1A1 | |
| SCHEMBL18630499 | 0.79 | ESR2 (0.59) | ESR2ESR1ELANEGAAPKM | |
| SCHEMBL4734126 | 0.78 | MMP2 (0.46) | ESR1ELANEGAAPKMHSD11B1 | |
| SCHEMBL25529698 | 0.78 | ELANE (0.44) | ESR2ESR1ELANEGAAPKM | |
| SCHEMBL537032 | 0.77 | GAA (0.54) | ELANEGAAPKMALDH1A1KMT2A | |
| SCHEMBL14942091 | 0.77 | GAA (0.54) | ESR1ELANEGAAPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665119-B1 | Thermochromic colour-memory composition | PILOT INK CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0665119-A1 | Thermochromic colour-memory composition | THE PILOT INK CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |