Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485925 | 0.86 | ALDH1A1 (0.48) | ALDH1A1NPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11977016 | 0.75 | LMNA (0.73) | ALDH1A1NPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12015824 | 0.74 | LMNA (0.75) | ALDH1A1NPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1758196 | 0.73 | ALDH1A1 (0.65) | ALDH1A1NPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL21883951 | 0.73 | MEN1 (0.52) | ALDH1A1NPSR1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2740260 | 0.73 | MEN1 (0.53) | ALDH1A1NPSR1POLBMEN1KMT2A | |
| SCHEMBL21883952 | 0.72 | NPSR1 (0.52) | ALDH1A1NPSR1POLBMEN1KMT2A | |
| SCHEMBL15636352 | 0.72 | MAPT (0.45) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL15296616 | 0.71 | NPSR1 (0.61) | ALDH1A1NPSR1HTR4HSD17B10MEN1 | |
| SCHEMBL15495475 | 0.71 | ALDH1A1 (0.54) | ALDH1A1NPSR1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |