Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TTK | P33981 | 2/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | ITK | Q08881 | 4/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672674 | 0.81 | IDO1 (0.78) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL3140348 | 0.77 | IDO1 (0.56) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL16720667 | 0.76 | IDO1 (0.50) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL16937122 | 0.73 | IDO1 (0.71) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL6112494 | 0.72 | ITK (0.51) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL855531 | 0.71 | ALDH1A1 (1.00) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL30768403 | 0.71 | ALDH1A1 (1.00) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL3712544 | 0.71 | KDM4E (0.62) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL374642 | 0.71 | KDM4E (0.32) | IDO1KDM4EGAAALDH1A1TTK | |
| SCHEMBL136316 | 0.71 | CYP1A2 (0.43) | IDO1KDM4EGAAALDH1A1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811629-A1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |