Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | IDO1 | P14902 | 3/20 | 1.00 |
| ▸ | MAPK10 | P53779 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | TTK | P33981 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | ALPL | P05186 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.68 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.62 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.62 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855531 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL17178615 | 0.96 | ALDH1A1 (0.92) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL27968462 | 0.92 | ALDH1A1 (0.85) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL1672674 | 0.88 | IDO1 (0.78) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL18977088 | 0.86 | TTK (0.75) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL10533662 | 0.85 | IDO1 (0.74) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL19597646 | 0.85 | TTK (0.72) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| Propionic Acid SCHEMBL4552403 | 0.84 | KDM4E (0.71) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL5377572 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KDM4EIDO1MAPK10GAA | |
| SCHEMBL4480025 | 0.84 | ALDH1A1 (0.71) | ALDH1A1KDM4EIDO1MAPK10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | THE UNIVERSITY OF THE WEST INDIES (TT) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382926-A1 | COMPOUNDS AND USES THEREOF | CFTR, CCL11, CEL | ALDH1A1 1002/4885KDM4E 4211/4885IDO1 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.