Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL877951 | 0.89 | CYP2C19 (0.53) | CYP2C19CPN1CPB2LMNAFOLH1 | |
| SCHEMBL7345071 | 0.84 | PTGS2 (0.52) | PTGS2CYP2C19CTSSCTSKACP3 | |
| SCHEMBL28710491 | 0.82 | MMP9 (0.51) | PTGS2CYP2C19FFAR1ABCC4LMNA | |
| SCHEMBL28980708 | 0.81 | PTGS2 (0.57) | PTGS2CYP2C19CTSSCTSKACP3 | |
| SCHEMBL30372175 | 0.81 | PTGS2 (0.57) | PTGS2CYP2C19CTSSCTSKACP3 | |
| SCHEMBL30372158 | 0.79 | PTGS2 (0.55) | PTGS2CYP2C19CTSSCTSKACP3 | |
| SCHEMBL17142353 | 0.79 | PTGS2 (0.55) | PTGS2CYP2C19CTSSCTSKACP3 | |
| SCHEMBL7565922 | 0.79 | PTGS2 (0.51) | PTGS2CTSSCTSKLMNAGAA | |
| SCHEMBL2014380 | 0.78 | PTGS2 (0.50) | PTGS2CYP2C19CTSSCTSKACP3 | |
| SCHEMBL3360072 | 0.78 | PTGS2 (0.46) | PTGS2CYP2C19CTSSCTSKACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619185-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038942-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |