Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056269 | 0.90 | CYP2C19 (0.49) | CYP2C19POLBLMNA | |
| SCHEMBL7345071 | 0.80 | PTGS2 (0.52) | PTGS2CTSSCTSKFFAR1CYP2C19 | |
| SCHEMBL5629157 | 0.78 | LMNA (0.41) | PTGS2FFAR1ACP3LMNACHRNB2 | |
| SCHEMBL28710491 | 0.78 | MMP9 (0.51) | PTGS2FFAR1CYP2C19ABCC4LMNA | |
| SCHEMBL877720 | 0.78 | PTGS2 (0.50) | PTGS2CTSSCTSKFFAR1CYP2C19 | |
| SCHEMBL1310192 | 0.78 | CHRNB2 (0.57) | PTGS2CTSSCTSKFFAR1CYP2C19 | |
| SCHEMBL8357747 | 0.77 | TBXAS1 (0.50) | CYP2C19POLB | |
| SCHEMBL28980708 | 0.77 | PTGS2 (0.57) | PTGS2CTSSCTSKFFAR1CYP2C19 | |
| SCHEMBL30372175 | 0.77 | PTGS2 (0.57) | PTGS2CTSSCTSKFFAR1CYP2C19 | |
| SCHEMBL30372158 | 0.75 | PTGS2 (0.55) | PTGS2CTSSCTSKFFAR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188264-A2 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009035150-A2 | 4-PHENYL-5-HYDROXY-3(2H)-PYRIDAZINONE DERIVATIVES AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |