Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 14/20 | 0.70 |
| ▸ | SLC1A2 | P43004 | 13/20 | 0.70 |
| ▸ | SLC1A3 | P43003 | 11/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777361 | 1.00 | SLC1A1 (0.70) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL7106222 | 0.82 | SLC1A2 (1.00) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL7106220 | 0.82 | SLC1A2 (1.00) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL2819524 | 0.82 | SLC1A2 (1.00) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL2819522 | 0.82 | SLC1A2 (1.00) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL9725774 | 0.81 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL18925992 | 0.81 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL288385 | 0.81 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL8464720 | 0.81 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL288386 | 0.81 | SLC1A1 (0.68) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810990-A1 | SUBSTITUTED DTPA MONOAMIDES OF CENTRAL CARBOXYLIC ACIDS AND METAL COMPLEXES THEREOF, PHARMACEUTICALS CONTAINING THESE COMPLEXES, DIAGNOSTIC AND THERAPEUTIC USES THEREOF AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5679852-A | Process for the production of DTPA-monoamides of the central carboxylic acid and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5676923-A | SOLUBLE, STABLE, ORGAN-SPECIFIC NUCLEAR MAGNETIC RESONANCE CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5676926-A | Process for the production of DTPA-tetraesters of terminal carboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| WO-1996026182-A1 | SUBSTITUTED DTPA MONOAMIDES OF CENTRAL CARBOXYLIC ACIDS AND METAL COMPLEXES THEREOF, PHARMACEUTICALS CONTAINING THESE COMPLEXES, DIAGNOSTIC AND THERAPEUTIC USES THEREOF AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-29 | — | — | WO | disclosed |
| US-5514810-A | Process for the production of DTPA-tetraesters of terminal carboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | disclosed |