SCHEMBL288386

SCHEMBL288386

C[C@@H](OCc1ccccc1)[C@H](N)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 10/20 0.68
SLC1A2 P43004 9/20 0.68
SLC1A3 P43003 8/20 0.68
MEN1 O00255 1/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2D6 P10635 1/20 0.68
CYP2C9 P11712 1/20 0.68
CYP2C19 P33261 1/20 0.68
KMT2A Q03164 1/20 0.68
SLC15A1 P46059 1/20 0.49
MMP9 P14780 2/20 0.47
MMP8 P22894 2/20 0.47
ALDH1A1 P00352 1/20 0.46
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
SLC7A5 Q01650 1/20 0.46
LTA4H P09960 1/20 0.44
RCE1 Q9Y256 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288385 1.00 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
SCHEMBL31606672 1.00 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
SCHEMBL18325959 1.00 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
SCHEMBL14037383 1.00 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
SCHEMBL289127 1.00 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
SCHEMBL8464720 1.00 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
SCHEMBL562232 1.00 SLC1A1 (0.68) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
Hydrochloric Acid SCHEMBL20820005 0.98 SLC1A1 (0.66) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
Hydrochloric Acid SCHEMBL15670199 0.98 SLC1A1 (0.66) SLC1A1SLC1A2SLC1A3MEN1CYP1A2
Hydrochloric Acid SCHEMBL3334189 0.98 SLC1A1 (0.66) SLC1A1SLC1A2SLC1A3MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270255-A1 CASPASE-2 INHIBITOR COMPOUNDS KINTSUGI THERAPEUTICS S L (ES) 2025-08-28 US claimed
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION WASHINGTON UNIVERSITY 2025-05-29 US claimed
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs DONG-A SOCIO HOLDINGS CO., LTD. (KR) 2025-01-14 US claimed
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ZEALAND PHARMA A/S (DK) 2024-09-03 US claimed
EP-4363436-A1 CASPASE-2 INHIBITOR COMPOUNDS Kintsugi Therapeutics S.L. (ES) 2024-05-08 EP claimed
CN-117940444-A Caspase-2 inhibitor compounds 金特速吉医疗有限责任公司 2024-04-26 CN claimed
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2023-12-21 US claimed
CN-116731101-A Derivatives of N-caproic acid-L-tyrosine-L-isoleucine- (6) -aminocaproamide for the treatment of various diseases 雅斯娜 2023-09-12 CN claimed
CN-116655730-A Derivatives of N-caproic acid-L-tyrosine-L-isoleucine- (6) -aminocaproamide for the treatment of various diseases 雅斯娜 2023-08-29 CN claimed
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ZEALAND PHARMA A/S (DK) 2023-08-01 US claimed
EP-0709373-B1 PYRROLIDINE DERIVATIVE ZAIDAN HOJIN BISEIBUTSU (JP) 2001-10-17 EP claimed
US-5753619-A CYCLIC HEPTAPEPTIDES FOR CARDIOVASCULAR DISORDERS TAKEDA CHEMICAL INSUSTRIES, LTD. (JP) 1998-05-19 US claimed
EP-0714909-A1 Composition for prophylaxis or treatment of pulmonary circulatory diseases Takeda Chemical Industries, Ltd. (JP) 1996-06-05 EP claimed
EP-0272671-B1 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD (CH) 1994-03-16 EP claimed
US-5055451-A Prevent tissue damage SYNTEX INC. (US) 1991-10-08 US claimed
EP-0272671-A2 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD. (CH) 1988-06-29 EP claimed
EP-0154581-B1 ALPHA-CHLORINATED CARBONATES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION TO THE PROTECTION OF AMINIC FUNCTIONS IN AMINO ACIDS SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1988-06-08 EP claimed
US-4483807-A Process for producing a slow release composite JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1984-11-20 US claimed
EP-0036713-B1 ANGIOTENSIN CONVERTING ENZYME INHIBITORS UNIVERSITY OF MIAMI (US) 1984-01-18 EP claimed
US-3936469-A Process for preparing N-carboxylic anhydrides of amino acids KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) 1976-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195446-B2 Heteroaryl compounds and their use as therapeutic drugs MERTK, ERBB2, SRC SLC1A1 2206/4885SLC1A2 2364/4885SLC1A3 2200/4885
US-20250270255-A1 CASPASE-2 INHIBITOR COMPOUNDS CASP2, CASP1, CASP3 SLC1A1 4633/4885SLC1A2 3886/4885SLC1A3 4619/4885
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION TMPRSS2, PRSS1, PRSS2 SLC1A1 3965/4885SLC1A2 4203/4885SLC1A3 4284/4885
US-12077611-B2 Cyclic peptides multimers targeting α4β7 integrin ITGB7, ITGB4, ITGA4 SLC1A1 2900/4885SLC1A2 4069/4885SLC1A3 3008/4885
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ITGB7, ITGB4, ITGA4 SLC1A1 3228/4885SLC1A2 4250/4885SLC1A3 3302/4885
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ITGB7, ITGB4, ITGA4 SLC1A1 3416/4885SLC1A2 4384/4885SLC1A3 3410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.